SARS-CoV Spike Protein (AA 14-1195) (His tag)
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- 抗原 See all SARS-CoV Spike (SARS-CoV S) 蛋白
- SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 14-1195
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宿主
- SARS Coronavirus (SARS-CoV)
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV Spike protein is labelled with His tag.
- 序列
- AA 14-1195
- 产品特性
- SARS S protein (R667A, K968P, V969P), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP13567.1(R667A, K968P, V969P). The recombinant protein is expressed with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (K968P, V969P) and alanine substitutions (R667A) are introduced to stabilize the trimeric prefusion state of SARS-CoV S protein and abolish the furin cleavage site, respectively.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV S 蛋白
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SARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (His-Avi Tag)
SARS-CoV S 宿主: SARS Coronavirus (SARS-CoV) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (His tag)SARS-CoV S 宿主: SARS Coronavirus (SARS-CoV) 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE.
> 95 % as determined by SEC-MALS. ELISA, SDSSARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (His-Avi Tag,Biotin)SARS-CoV S 宿主: SARS Coronavirus (SARS-CoV) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SARS-Coronavirus Spike Protein (SARS-CoV S) (RBD) protein (mFc Tag)SARS-CoV S 宿主: SARS Coronavirus (SARS-CoV) 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE.
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS
- 储存条件
- -20 °C
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- 抗原
- SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
- 别名
- SARS S protein (SARS-CoV S 产品)
- 物质类
- Viral Protein
- 背景
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- 分子量
- 136.3 kDa
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