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beta Actin 抗体 (AA 1-50)

Name: beta Actin 抗体 (AA 1-50)
SKU: ABIN724340
Availability: OutOfStock

ACTB 适用: 人, 小鼠, 大鼠, 兔, Pig, Cow WB, ELISA, IHC (p), FACS, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

NLRP3 inflammasome activation was involved in P2Y14R deficiency.

Rat lung lysate 30ug, probed (ABIN724340) at 1:200 overnight in 4 °C.

SDS

Image kindly submitted by Piotr Mamczur from Wroclaw University.

Human HeLa cell lysates probed with Rabbit Anti-beta Actin Polyclonal Antibody, Unconjugated .

FACS

IF (cc)

Hepatic overexpression of HNF4α in rats decreased cholesterol levels in both plasma and liver.

Expression pattern of hepatic cholesterol-regulatory genes under HNF4α overexpression in rat liver.

HNF4α-upregulated SR-BI depends on PPARγ.

High-temperature cultivation of an rhIL-10 expression strain impairs the maturation of G3-pro-rhIL10.

High-temperature cultivation of an rhIL-10 expression strain impairs ER folding capacity.

(a) Expression of viral N (Nucleoprotein) and G (Glycoprotein) genes mRNA in zebrafish embryonic fibroblast cell line (ZF4) with time after snakehead fish vesiculovirus (SHVV) infection.

Expression of Mx and interferon (IFN) genes in ZF4 with time after SHVV infection.

Expression of Retinoic acid-inducible gene I (RIG-I), Melanoma differentiation-associated gene 5 (MDA5), LGP2T, and LGP2a genes in ZF4 with time after SHVV infection.

(a) The expression of DrLGP2a, DrLGP2b proteins during the infection with SHVV.

Pro-Gly, but not Pro plus Gly (Pro+Gly), promoted the expression and secretion of IGF-1 in the HepG2 cells.

Knockdown of PepT1 eliminated the increase of IGF-1 expression induced by Pro-Gly in the HepG2 cells.

Pro-Gly activated JAK2/STAT5 signaling pathway in a PepT1-dependent manner.

Inhibition of JAK2/STAT5 signaling pathway blocked the promotive effect of Pro-Gly on IGF-1 expression and secretion in the HepG2 cells.

Acute or chronic injection of Pro-Gly, but not Pro plus Gly (Pro+Gly), stimulated IGF-1 expression and secretion in mice.

Injection of JAK2/STAT5 inhibitor abolished the promotive effect of Pro-Gly on IGF-1 expression and secretion in mice.

Protein expression of MTA1 by Western Blot analysis.

Effects of stable YAP1 silencing in BGC-823 cells and stable YAP1 overexpressing in GES-1 cells on migration and invasion abilities in vitroThe wound healing assay was used to evaluate the migration properties of BGC-823 GC cells (A, G) and GES-1 cells (B, H).

Effects of JQ1 treatment on cell proliferation, migration and invasion in ccRCC cell lines(A) Cell proliferation was determined by XTT assays (*P < 0.

JQ1 treatment inhibited MYC expression in ccRCC cells(A) The expression level of MYC mRNA was significantly upregulated in ccRCC tissues compared with that in normal kidney tissues according to TCGA data (P < 0.

Protein levels of NF-κB and NLRP3/Caspase-1 pathway in CIA rats.

Clinical significance of BRD4 expression in ccRCC according to TCGA data(A) Overall survival (OS) was significantly shortened in patients with high BRD4 expression (top third) compared with that in patients with medium and low BRD4 expression (P = 0.

The effect of LBP on the expression of GFAP, VEGF, and PEDF in the retinal tissue.

Relative expression of AANAT, HIOMT, MT1, and MT2 in COCs of follicles of different sizes.

Effect of E2 and ER antagonist ICI182780 on melatonin production and the expression of AANAT, HIOMT, MT1, and MT2 mRNA and protein in sheep COCs.

Arginine inhibits HIF-1α to reduce LDHA expression after cerebral I/R injury.

Upregulated cAMP suppressed acute gouty arthritis in vivo.

Pyroptosis stress was invalidated once cAMP increased by Forskolin in vitro.

Decreased cAMP exaggerated acute gouty arthritis in P2Y14R-KO rats.

43 images

(270 references)

产品编号 ABIN724340

发货至: 中国

Datasheet as PDF

Key Features
- High quality beta Actin Primary Antibody for the detection of ACTB.
- Reliable product with high standard validation data
抗原 See all beta Actin (ACTB) 抗体

beta Actin (ACTB) (Actin, beta (ACTB))
抗原表位
40

18

15

6

6

5

5

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-50
适用
191

132

119

63

51

43

37

35

32

25

20

20

12

10

9

8

7

6

5

5

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 兔, Pig, Cow
宿主
115

92

5

2

1
兔
Compatible Secondaries
克隆类型
109

104
多克隆
标记
132

15

14

10

4

4

4

4

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1
This beta Actin antibody is un-conjugated
应用范围
180

75

58

53

36

36

27

24

12

12

7

6

6

5

4

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

交叉反应

Cow, 犬, 山羊, 人, 小鼠, Pig, 兔, 大鼠, 绵羊, Various Species

纯化方法

Purified by Protein A.

免疫原

MAP conjugated synthetic peptide derived from human beta Actin

亚型

IgG

Product Specific Information

What can the beta Actin Antibody ABIN724340 be used for?

This polyclonal beta Actin Antibody detects beta Actin. The beta Actin Antibody has been validated for various applications and can be used for the detection of beta Actin and derivatives by Western Blotting, ELISA, Immunohistochemistry (Paraffin-embedded Sections), Flow Cytometry, Immunofluorescence (Paraffin-embedded Sections), Immunofluorescence (Cultured Cells).

What validation data is available for this beta Actin Antibody?

The Primary Antibody is referenced in 254 publications and is characterized by a proven, very high reliability. It has currently 43 product images that show its performance in a variety of applications. beta Actin Antibody for the detection of beta Actin and derivatives.

What is the function of beta Actin?

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008].
anti-Actin, beta (ACTB) antibody
ACTB 适用: 人 WB, IF, IP 宿主: 小鼠 Monoclonal unconjugated

anti-Actin, beta (ACTB) (AA 359-368) antibody
ACTB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) (AA 2-16) antibody
ACTB 适用: 小鼠, 大鼠, 小鸡, 斑马鱼 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) (AA 1-25) antibody
ACTB 适用: 人, 小鼠, 大鼠, Pig, Cow WB, IHC (p) 宿主: 小鼠 Monoclonal 1A2 unconjugated

anti-Actin, beta (ACTB) (AA 1-375) antibody
ACTB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G4-F9 unconjugated

anti-Actin, beta (ACTB) (AA 1-375) antibody
ACTB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) (N-Term) antibody
KO Validated ACTB 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Actin, beta (ACTB) antibody
ACTB 适用: 人, 小鼠, 小鸡, 兔, Pig, Cow, Hamster, 山羊, 鱼 WB, ELISA 宿主: 小鼠 Monoclonal 2D1D10 unconjugated

anti-Actin, beta (ACTB) antibody
ACTB 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS, DNA Mic 宿主: 小鼠 Monoclonal 137CT26-1-1 unconjugated

anti-Actin, beta (ACTB) (AA 1-50) antibody
ACTB 适用: 人 WB, ELISA, IHC, IF, IP, FACS 宿主: 小鼠 Monoclonal 1D12E12B5 unconjugated

应用备注

WB 1:100-1000
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
Chen, Pan, Tang, Cheng, Zhao, Zhang, Liao, Liu, Zhuang, Zhang, Chen, Lei, Li, Li, Wang, Wan: "Arginine is neuroprotective through suppressing HIF-1α/LDHA-mediated inflammatory response after cerebral ischemia/reperfusion injury." in: Molecular brain, Vol. 13, Issue 1, pp. 63, (2021) (PubMed).

Li, Jiang, Ye, Zhou, Liu, Yang, Hao, Hu: "P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages." in: Cell death & disease, Vol. 11, Issue 5, pp. 394, (2021) (PubMed).

Yang, Tang, Wang, Zhang, Zan: "Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes." in: Scientific reports, Vol. 7, Issue 1, pp. 15080, (2019) (PubMed).

Huang, Zhu, Yi, Yan, Wei, Yang, Chen, Huang: "A novel TRAIL mutant-TRAIL-Mu3 enhances the antitumor effects by the increased affinity and the up-expression of DR5 in pancreatic cancer." in: Cancer chemotherapy and pharmacology, Vol. 82, Issue 5, pp. 829-838, (2019) (PubMed).

Lai, Jiang, Xie, Liu, Tang, Xiao, Gao, Jia, Bai: "Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Mouse Model of Parkinson's Disease." in: Neurochemical research, Vol. 43, Issue 10, pp. 1986-1999, (2019) (PubMed).

Li, Feng, Hu, Chen, Sha, Zhang, Fan: "Effect of melatonin on attenuating the isoflurane-induced oxidative damage is related to PKCα/Nrf2 signaling pathway in developing rats." in: Brain research bulletin, Vol. 143, pp. 9-18, (2019) (PubMed).

Jia, Kong, Guo, Li, Quan: "Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo." in: Biochemical and biophysical research communications, Vol. 505, Issue 3, pp. 720-725, (2019) (PubMed).

Zhang, Li, Fu, Lin, Lin, Tu: "MiR-214 inhibits snakehead vesiculovirus (SHVV) replication by targeting host GS." in: Fish & shellfish immunology, Vol. 84, pp. 299-303, (2019) (PubMed).

Song, Ma, Hua, Xu, Li, Ju, Hou: "Functional role of RRS1 in breast cancer cell proliferation." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6304-6313, (2019) (PubMed).

Feng, Su, Lin, Tu: "Development of a reverse genetics system for snakehead vesiculovirus (SHVV)." in: Virology, Vol. 526, pp. 32-37, (2019) (PubMed).

Cui, Xing, Huang, Li, Lu, Wang, Wang, Huang, Cheng, Hao, Peng, Liu, Dai, Yuan: "Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox." in: Biomedicine & pharmacotherapy, Vol. 108, pp. 1879-1893, (2019) (PubMed).

Voogdt, Merchant, Wagenaar, van Putten: "Evolutionary Regression and Species-Specific Codon Usage of TLR15." in: Frontiers in immunology, Vol. 9, pp. 2626, (2019) (PubMed).

Zhang, Do, Chandimali, Lee, Mok, Kim, Kim, Kwon, Jeong: "Non-thermal plasma treatment improves chicken sperm motility via the regulation of demethylation levels." in: Scientific reports, Vol. 8, Issue 1, pp. 7576, (2019) (PubMed).

Pang, Wang, Ran, Lin, Wang, Guan, Yuan, Fang, Liu, Wang et al.: "Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass ..." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

Zhang, Zhao, Li, Li: "Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia." in: Brain research bulletin, Vol. 146, pp. 136-142, (2019) (PubMed).

Xia, Qu, Jia, He, Li, Zhao, Mao, Zhao: "Overexpression of Forkhead box C1 attenuates oxidative stress, inflammation and apoptosis in chronic obstructive pulmonary disease." in: Life sciences, Vol. 216, pp. 75-84, (2019) (PubMed).

Su, Tian, Liu, Ci, Lv: "Purinergic P2X7 receptor blockade mitigates alcohol-induced steatohepatitis and intestinal injury by regulating MEK1/2-ERK1/2 signaling and egr-1 activity." in: International immunopharmacology, Vol. 66, pp. 52-61, (2019) (PubMed).

Xiao, Hu, Song, Zhang, Dong, Jiang, Zhang, Yuan, Zhao: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." in: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).

Ommati, Heidari, Jamshidzadeh, Zamiri, Sun, Sabouri, Wang, Ahmadi, Javanmard, Seifi, Mousapour, Yeganeh: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." in: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).

Liu, Liu, Bai, Zhang, Ma, Yang, Sun: "Hypoxia-induced activation of Twist/miR-214/E-cadherin axis promotes renal tubular epithelial cell mesenchymal transition and renal fibrosis." in: Biochemical and biophysical research communications, Vol. 495, Issue 3, pp. 2324-2330, (2018) (PubMed).

show more references
抗原

beta Actin (ACTB) (Actin, beta (ACTB))

别名

beta Actin (ACTB 产品)

别名

BRWS1 antibody, PS1TP5BP1 antibody, ACTA1 antibody, Actx antibody, E430023M04Rik antibody, beta-actin antibody, ps1tp5bp1 antibody, act-2 antibody, actb antibody, B-actin antibody, LOC100174883 antibody, LOC100304816 antibody, A antibody, ACT5C antibody, Ac5C antibody, Act antibody, Act-5C antibody, Act5 antibody, Act5c antibody, Actin antibody, Actin/BAP47 antibody, Actin5C antibody, BAP47 antibody, Bap47 antibody, CG4027 antibody, Dmel\\CG4027 antibody, M32055 antibody, T11 antibody, act antibody, act 5C antibody, act5C antibody, actin antibody, actin5C antibody, anon-EST:fe2D2 antibody, beta-actin/Bap47 antibody, cyt5C antibody, l(1)G0009 antibody, l(1)G0010 antibody, l(1)G0025 antibody, l(1)G0079 antibody, l(1)G0117 antibody, l(1)G0177 antibody, l(1)G0245 antibody, l(1)G0330 antibody, l(1)G0420 antibody, l(1)G0486 antibody, Bact antibody, ACT-5 antibody, ACTB antibody, B-ACTZF antibody, actba antibody, bact antibody, bactin1 antibody, bactzf antibody, wu:fd18f05 antibody, A26C1B antibody, POTE2alpha antibody, POTEACTIN antibody, Beta-actin antibody, actin beta antibody, actin, beta antibody, cytoplasmic actin OlCA1 antibody, beta-actin antibody, Actin 5C antibody, actin gamma 1 antibody, actin, beta 1 antibody, actin, beta L homeolog antibody, beta actin antibody, POTE ankyrin domain family member F antibody, actin, beta like 2 antibody, actin, cytoplasmic 1 antibody, ACTB antibody, Actb antibody, actb antibody, LOC100174883 antibody, LOC100304816 antibody, Act5C antibody, ACTG1 antibody, actb1 antibody, actb.L antibody, LOC100136352 antibody, POTEF antibody, ACTBL2 antibody, LOC109073280 antibody

背景

Synonyms: BRWS1, PS1TP5BP1, Actin, cytoplasmic 1, Beta-actin, ACTB
Background: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

基因ID

60

UniProt

P60709

途径

Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction