MADCAM1 Protein (AA 19-333) (Fc Tag)
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- 抗原 See all MADCAM1 蛋白
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 19-333
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MADCAM1 protein is labelled with Fc Tag.
- 原理
- Human MAdCAM-1 Protein, Fc Tag (MALS verified)
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MADCAM1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- 别名
- MAdCAM-1 (MADCAM1 产品)
- 别名
- MACAM1 Protein, AV211525 Protein, mucosal vascular addressin cell adhesion molecule 1 Protein, MADCAM1 Protein, Madcam1 Protein
- 背景
- The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.
- 分子量
- 59.6 kDa
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