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CD43 Protein (Fc Tag)

SPN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6964395
发货至: 中国
  • 抗原 See all CD43 (SPN) 蛋白
    CD43 (SPN) (Sialophorin (SPN))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 6
    • 1
    • 1
    资源
    • 6
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD43 protein is labelled with Fc Tag.
    原理
    Recombinant Human CD43 Protein with C-terminal human Fc tag
    特异性
    CD43 (Ser20-Arg253) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product SPN 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CD43 (SPN) (Sialophorin (SPN))
    别名
    CD43 (SPN 产品)
    别名
    CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
    背景
    Synonymes: CD43, GALGP, GPL115, LSN
    Description: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
    分子量
    predicted molecular mass of 49.6 kDa after removal of the signal peptide.The apparent molecular mass of CD43-hFc is 55-130 kDa due to glycosylation.
    UniProt
    P16150
    途径
    Regulation of Leukocyte Mediated Immunity
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