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CCR3 Protein (Fc Tag)

CCR3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6964390
发货至: 中国
  • 抗原 See all CCR3 蛋白
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CCR3 protein is labelled with Fc Tag.
    原理
    Recombinant human CCR3 protein with C-terminal human Fc tag
    特异性
    CCR3 (Met1-Ala34) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CCR3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CCR3 (CCR3 产品)
    别名
    CC-CKR-3 Protein, CD193 Protein, CKR3 Protein, CMKBR3 Protein, CC-CKR3 Protein, Cmkbr1l2 Protein, Cmkbr3 Protein, C-C motif chemokine receptor 3 Protein, chemokine (C-C motif) receptor 3 Protein, CCR3 Protein, Ccr3 Protein
    背景
    Synonymes: CC-CKR-3, CD193, CKR3, CMKBR3
    Description: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
    分子量
    predicted molecular mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of CCR3-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P51677
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