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P2RX7 Protein (Fc Tag)

P2RX7 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6964308
发货至: 中国
  • 抗原 See all P2RX7 蛋白
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    资源
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This P2RX7 protein is labelled with Fc Tag.
    原理
    Recombinant human P2RX7 protein with N-terminal human Fc tag
    特异性
    HFc (Glu99-Ala330) P2RX7 (Ser47-Val334)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product P2RX7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    别名
    P2RX7 (P2RX7 产品)
    别名
    p2xr7 Protein, P2RX7 Protein, P2X7 Protein, AI467586 Protein, P2X(7) Protein, P2X7R Protein, p2x7 Protein, purinergic receptor P2X 7 Protein, purinergic receptor P2X, ligand-gated ion channel, 7 Protein, P2X purinoceptor 7 Protein, P2RX7 Protein, p2rx7 Protein, LOC100458463 Protein, P2rx7 Protein
    背景
    The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
    分子量
    predicted molecular mass of 59.2 kDa after removal of the signal peptide. The apparent molecular mass of hFc-P2RX7 is 55-70 kDa due to glycosylation.
    UniProt
    Q99572
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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