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CD8 alpha Protein (Fc Tag)

This Recombinant CD8 alpha protein is expressed in HEK-293 Cells.
产品编号 ABIN6964139
发货至: 中国

Quick Overview for CD8 alpha Protein (Fc Tag) (ABIN6964139)

抗原

See all CD8 alpha (CD8A) 蛋白
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells
  • 标记

    This CD8 alpha protein is labelled with Fc Tag.

    序列

    CD8A(Ser22-Asp182)+hFc(Glu99-Ala330)

    产品特性

    Tagged Protein: C-Human Fc tag

    纯化方法

    affinity purification
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with deionized water

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存液

    Without preservative

    储存条件

    -80 °C

    储存方法

    Store at -80°C for 12 months (Avoid repeated freezing and thawing)

    有效期

    12 months
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8A

    背景

    Synonymes: CD8, Leu2, p32
    Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.

    分子量

    43.23 kDa

    UniProt

    P01732

    途径

    TCR Signaling
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