CD8 alpha Protein (Fc Tag)
Our Local Distributor
北京 101111
Quick Overview for CD8 alpha Protein (Fc Tag) (ABIN6964139)
抗原
See all CD8 alpha (CD8A) 蛋白蛋白类型
宿主
资源
-
-
标记
- This CD8 alpha protein is labelled with Fc Tag.
-
序列
- CD8A(Ser22-Asp182)+hFc(Glu99-Ala330)
-
产品特性
- Tagged Protein: C-Human Fc tag
-
纯化方法
- affinity purification
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute with deionized water
-
缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
储存液
- Without preservative
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
-
有效期
- 12 months
-
-
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
-
别名
- CD8A
-
背景
-
Synonymes: CD8, Leu2, p32
Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. -
分子量
- 43.23 kDa
-
UniProt
- P01732
-
途径
- TCR Signaling
抗原
-