This SARS-CoV-2 NSP3 protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
原理
SARS-CoV-2 (COVID-19) Papain-like Protease Protein, His Tag
序列
AA 746-1060
产品特性
SARS-CoV-2 Papain-like Protease, His Tag is expressed from E.coli cells. It contains AA Glu 746 - Lys 1060 (Accession # YP_009725299.1). Predicted N-terminus: Met This protein carries a polyhistidine tag at the N-terminus.
pp1ab Protein, ORF1a polyprotein;ORF1ab polyprotein Protein, ORF1ab Protein
物质类
Viral Protein
背景
New coronavirus is a single-stranded RNA positive-strand envelope type B coronavirus. Similar to the other two coronaviruses that cause SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome), its genome encodes non-structural, structural, and accessory proteins. Non-structural proteins include 3-chymotrypsin-like protease (3CLpro), papain-like protease, helicase, and RNA-dependent RNA polymerase (RNA -dependent RNA polymerase (RdRp). Structural proteins include spike glycoproteins. Papain in coronavirus is the same as 3CLpro. This enzyme operates on no less than 11 cleavage sites on the large polyprotein 1ab. Processing of polyproteins translated from viral RNA is essential. Therefore, press this The activity of this enzyme will prevent virus imitation.