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SARS-CoV S1 Protein (His tag)

SARS-CoV S1 宿主: SARS Coronavirus (SARS-CoV) 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. SDS, ELISA
产品编号 ABIN6952622
发货至: 中国
  • 抗原 See all SARS-CoV S1 products
    SARS-CoV S1 (SARS-Coronavirus Spike Subunit S1 (SARS-CoV S1))
    蛋白类型
    Recombinant
    宿主
    • 1
    • 1
    SARS Coronavirus (SARS-CoV)
    资源
    • 2
    HEK-293 Cells
    标记
    This SARS-CoV S1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS), ELISA
    原理
    SARS S1 protein, His Tag (MALS verified)
    序列
    AA 14-667
    产品特性
    SARS S1 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Arg 667 (Accession # AAP13567.1). Predicted N-terminus: Ser 14
    This protein carries a polyhistidine tag at the C-terminus.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    This product is stable after storage at:
    4-8°C for 12 months in lyophilized state,
    -70°C for 3 years under sterile conditions after reconstitution.
  • Kondo, Iwatani, Matsuoka, Fujino, Umemoto, Yokomaku, Ishizaki, Kito, Sezaki, Hayashi, Murakami: "Antibody-like proteins that capture and neutralize SARS-CoV-2." in: Science advances, Vol. 6, Issue 42, (2020) (PubMed).

    Tosif, Neeland, Sutton, Licciardi, Sarkar, Selva, Do, Donato, Quan Toh, Higgins, Van de Sandt, Lemke, Lee, Shoffner, Flanagan, Arnold, Mordant, Mulholland, Bines, Dohle, Pellicci, Curtis, McNab et al.: "Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19. ..." in: Nature communications, Vol. 11, Issue 1, pp. 5703, (2020) (PubMed).

  • 抗原
    SARS-CoV S1 (SARS-Coronavirus Spike Subunit S1 (SARS-CoV S1))
    别名
    SARS-Coronavirus Spike Subunit S1 (SARS-CoV S1 产品)
    物质类
    Viral Protein
    背景
    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    分子量
    74.9 kDa
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