Macrophage Mannose Receptor 1 Protein (AA 19-1389) (His tag)
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- 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 蛋白
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-1389
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Macrophage Mannose Receptor 1 protein is labelled with His tag.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MRC1 蛋白
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Mannose Receptor, C Type 1 (MRC1) (AA 19-148) protein (His-IF2DI Tag)
MRC1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Mannose Receptor, C Type 1 (MRC1) (AA 22-130) protein (GST tag)MRC1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mannose Receptor, C Type 1 (MRC1) (AA 19-1389) protein (His tag)Crystallography grade MRC1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Mannose Receptor, C Type 1 (MRC1) (AA 20-1388) protein (His tag)Crystallography grade MRC1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Mannose Receptor, C Type 1 (MRC1) (AA 19-1456) protein (rho-1D4 tag)Crystallography grade MRC1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Mannose Receptor, C Type 1 (MRC1) (AA 20-1456) protein (rho-1D4 tag)Crystallography grade MRC1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Mannose Receptor, C Type 1 (MRC1) (AA 655-1213), (partial) protein (His tag)MRC1 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 别名
- CD206 (MRC1 产品)
- 别名
- CD206 Protein, CLEC13D Protein, CLEC13DL Protein, MMR Protein, MRC1L1 Protein, bA541I19.1 Protein, AW259686 Protein, MR Protein, mrc1 Protein, MGC86525 Protein, MRC1 Protein, MRC1L-A Protein, mannose receptor C-type 1 Protein, mannose receptor, C type 1 Protein, mannose receptor C-type 1 L homeolog Protein, mediator of replication checkpoint 1 Protein, MRC1 Protein, Mrc1 Protein, mrc1.L Protein, mrc1 Protein
- 背景
- Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumor-associated macrophages (TAMs) expressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse.
- 分子量
- 158.6 kDa
- NCBI登录号
- NP_002429
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