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MUC1 Protein (AA 890-1158) (His tag)

MUC1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN6950993
发货至: 中国
  • 抗原 See all MUC1 蛋白
    MUC1 (Mucin 1 (MUC1))
    蛋白类型
    Recombinant
    产品特性
    AA 890-1158
    宿主
    • 27
    • 8
    • 3
    • 3
    • 2
    资源
    • 14
    • 13
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This MUC1 protein is labelled with His tag.
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product MUC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    Mucin-1 (MUC1 产品)
    别名
    CA 15-3 Protein, CD227 Protein, EMA Protein, H23AG Protein, KL-6 Protein, MAM6 Protein, MCKD1 Protein, MUC-1 Protein, MUC-1/SEC Protein, MUC-1/X Protein, MUC1/ZD Protein, PEM Protein, PEMT Protein, PUM Protein, Muc-1 Protein, mucin 1, cell surface associated Protein, mucin 1, transmembrane Protein, MUC1 Protein, Muc1 Protein
    背景
    Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
    分子量
    21.3 kDa (partial α chain) & 8.4 kDa (partial β chain)
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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