IGSF11 Protein (AA 23-241) (Fc Tag)
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- 抗原 See all IGSF11 蛋白
- IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 23-241
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IGSF11 protein is labelled with Fc Tag.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IGSF11 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
- 别名
- VSIG3 (IGSF11 产品)
- 别名
- sc:d812 Protein, seurat Protein, BT-IgSF Protein, CT119 Protein, CXADRL1 Protein, Igsf13 Protein, VSIG3 Protein, 1700025L02Rik Protein, immunoglobulin superfamily member 11 Protein, immunoglobulin superfamily member 11 L homeolog Protein, immunoglobulin superfamily, member 11 Protein, IGSF11 Protein, igsf11 Protein, igsf11.L Protein, Igsf11 Protein
- 背景
- VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.
- 分子量
- 49.7 kDa
- NCBI登录号
- NP_001015887
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