Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 39-426) protein (His tag)
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- 抗原 See all Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) 蛋白
- Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB)
- 蛋白类型
- Recombinant
- 产品特性
- AA 39-426
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- His tag
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CBLB 蛋白
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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 1-982) protein (GST tag)
CBLB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 39-426) protein (His tag)CBLB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 21-129) protein (GST tag)CBLB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) protein (Myc-DYKDDDDK Tag)CBLB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 40 mM HEPES, 120 mM NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB)
- 别名
- CBLB (CBLB 产品)
- 别名
- rnf56 Protein, cblb Protein, AI429560 Protein, AI851073 Protein, Cbl-b Protein, Cbl proto-oncogene B, E3 ubiquitin protein ligase S homeolog Protein, Cbl proto-oncogene B, E3 ubiquitin protein ligase L homeolog Protein, Casitas B-lineage lymphoma b Protein, Cbl proto-oncogene B Protein, cblb.S Protein, cblb.L Protein, Cblb Protein, CBLB Protein
- 背景
- Casitas B-lineage lymphoma proto-oncogene b (CBLB) is also known as RNF56. E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways. Slightly promotes SRC ubiquitination. May be involved in EGFR ubiquitination and internalization. May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3. Expressed in placenta, heart, lung, kidney, spleen, ovary and testis, as well as fetal brain and liver and hematopoietic cell lines, but not in adult brain, liver, pancreas, salivary gland, or skeletal muscle.
- 分子量
- 47.0 kDa
- NCBI登录号
- NP_733762
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