IL-15 Protein (AA 49-162) (Fc Tag,AVI tag,Biotin)
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- 抗原 See all IL-15 (IL15) 蛋白
- IL-15 (IL15) (Interleukin 15 (IL15))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 49-162
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL-15 protein is labelled with Fc Tag,AVI tag,Biotin.
- 序列
- AA 49-162
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product IL15 蛋白
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Interleukin 15 (IL15) protein
IL15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by SEC-HPLC
Interleukin 15 (IL15) (AA 50-162) (Active) protein (His tag)IL15 宿主: 人 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
Interleukin 15 (IL15) (AA 49-162) protein (His-IF2DI Tag)IL15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 15 (IL15) (AA 49-162) protein (His-IF2DI Tag)IL15 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 15 (IL15) (AA 1-162) protein (GST tag)IL15 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 15 (IL15) (AA 30-129) protein (GST tag)IL15 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 15 (IL15) (AA 49-162) (Active) protein (His tag)IL15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Interleukin 15 (IL15) proteinIL15 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant
Interleukin 15 (IL15) (AA 49-162) (Active) protein (Fc Tag)IL15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 15 (IL15) (AA 49-162) (Active) protein (His tag)IL15 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- IL-15 (IL15) (Interleukin 15 (IL15))
- 别名
- IL-15 (IL15 产品)
- 别名
- IL15 Protein, AI503618 Protein, IL-15 Protein, interleukin 15 Protein, IL15 Protein, Il15 Protein
- 背景
- Interleukin 15 is also known as IL15, IL-15, and is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells, cells of the innate immune system whose principal role is to kill virally infected cells. Interleukin 15 (IL-15) regulates T and natural killer (NK) cell activation and proliferation. Survival signals that maintain memory T cells in the absence of antigen are provided by IL-15. This cytokine is also implicated in NK cell development. In rodent lymphocytes, IL-15 prevents apoptosis by inducing an apoptosis inhibitor, BCL2L1/BCL-x(L). IL-15 has been shown to enhance the anti-tumor immunity of CD8+ T cells in pre-clinical models. A phase I clinical trial to evaluate the safety, dosing, and anti-tumor efficacy of IL-15 in patients with metastatic melanoma and renal cell carcinoma (kidney cancer) has begun to enroll patients at the National Institutes of Health.
- 分子量
- 41.0 kDa
- NCBI登录号
- NP_000576
- 途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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