TGFB1 蛋白
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- 抗原 See all TGFB1 蛋白
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- CHO Cells
- Supplier Product No.
- 009-001-w26-0005
- Supplier
- Rockland
- 原理
- Human Transforming Growth Factor beta 1 Recombinant Protein
- 纯化方法
- Transforming Growth Factor beta 1 purity was determined to be greater than 98% as determined by reducing and non-reducing SDS-pAGE.
- 纯度
- 98,00%
- 内毒素水平
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- The activity is measured by the dose-dependent inhibition of IL-4-induced proliferation from mouse HT-2 cells and is typically 0.04-0.2 ng/mL.
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- Discover our top product TGFB1 蛋白
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- 应用备注
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Other: User Optimized
Application_Note: Transforming Growth Factor beta 1 Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Transforming Growth Factor beta 1 in immunological assays.
- 说明
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Suggested_Applications: Cellular Assay
Other_Performance_Data:
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 5 μL (5-50 μL)
- 浓度
- 0.1 mg/mL
- 缓冲液
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Buffer: 0.1 % Trifluoroacetic acid
Stabilizer: None
- 储存液
- Without preservative
- 储存条件
- -20 °C
- 储存方法
- Store vial at -20° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative, it does contain Trehalose in a ratio of 20:1 (Trehalose:Protein) DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- 有效期
- 6 months
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- 抗原
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- 别名
- TGFB1 (TGFB1 产品)
- 背景
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Synonyms: Differentiation inhibiting factor, cartilage-inducing factor
Background: Transforming Growth Factor-beta 1 (TGF-β1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-β1 signals through SMAD proteins via the TGF-β1 RI and RII receptors. Mature human TGF-β1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25 kDa.
- UniProt
- P01137
- 途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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