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GMP Synthase Protein (AA 1-693) (His tag)

GMPS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN668022
发货至: 中国
  • 抗原 See all GMP Synthase (GMPS) 蛋白
    GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
    蛋白类型
    Recombinant
    产品特性
    AA 1-693
    宿主
    • 5
    • 1
    • 1
    资源
    • 2
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    • 1
    大肠杆菌(E. Coli)
    标记
    This GMP Synthase protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    GMPS, 1-693aa , Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
    储存条件
    4 °C
  • 抗原
    GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
    别名
    GMPS (GMPS 产品)
    别名
    GMPS Protein, AA591640 Protein, AI047208 Protein, sb:cb632 Protein, wu:fb76b01 Protein, wu:fi05a09 Protein, zgc:66002 Protein, guanine monophosphate synthase Protein, guanine monophosphate synthase L homeolog Protein, guanine monophosphate synthetase Protein, GMPS Protein, gmps.L Protein, gmps Protein, Gmps Protein
    背景
    GMP synthase, also known as GMPS, is involved in purine biosynthesis. Existing as a homodimer, GMPS catalyzes the last step in the GMP synthesis pathway, namely the ATP-dependent amination of XMP to GMP. GMPS contains one GMP-binding domain and one glutamine amidotransferase type-1 domain through which it conveys its catalytic activity. Chromosomal translocations involving the gene encoding GMPS are associated with acute myeloid leukemias, suggesting a possible role for GMPS in carcinogenesis. Recombinant human GMPS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GMP synthase [glutamine-hydrolyzing], Glutamine amidotransferase, guanine monophosphate synthetase. NCBI no.: NP_003866
    分子量
    79.2 kDa (717aa)
    途径
    Ribonucleoside Biosynthetic Process
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