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DUSP10 Protein (AA 149-482) (His tag)

DUSP10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN668018
发货至: 中国
  • 抗原 See all DUSP10 蛋白
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    蛋白类型
    Recombinant
    产品特性
    AA 149-482
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This DUSP10 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    DUSP10, 149-482aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl
    储存条件
    4 °C
  • 抗原
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    别名
    DUSP10 (DUSP10 产品)
    别名
    DUSP10 Protein, MKP-5 Protein, MKP5 Protein, 2610306G15Rik Protein, AI158871 Protein, Mkp-5 Protein, Mkp5 Protein, dual specificity phosphatase 10 Protein, DUSP10 Protein, Dusp10 Protein
    背景
    DUSP10 (Dual specificity protein phosphatase 10) belongs to the protein-tyrosine phosphatase family. Dual specificity protein phosphatases(DUSPs) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. DUSP10 has been shown to interact with MAPK14 and MAPK8. When expressed in mammalian cells, DUSP10 blocks the enzymatic activation of MAP kinases with the selectivity p38 approximately JNK/SAPK >> ERK. Recombinant human DUSP10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Dual specificity protein phosphatase 10, MKP-5, MKP5. NCBI no.: NP_009138
    分子量
    40.4kDa (359aa), confirmed by MALDI-TOF
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