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GNB2L1 Protein (AA 1-317) (His tag)

GNB2L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN668010
发货至: 中国
  • 抗原 See all GNB2L1 蛋白
    GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-317
    宿主
    • 6
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    资源
    • 9
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    大肠杆菌(E. Coli)
    标记
    This GNB2L1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    GNB2L1, 1-317aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GNB2L1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 0.2M NaCl, 5mM DTT
    储存条件
    4 °C
  • 抗原
    GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
    别名
    GNB2L1 (GNB2L1 产品)
    别名
    MGC53289 Protein, GNB2L1 Protein, AL033335 Protein, GB-like Protein, Gnb2-rs1 Protein, Rack1 Protein, p205 Protein, RACK1 Protein, H12.3 Protein, HLC-7 Protein, PIG21 Protein, rack1 Protein, wu:fb80d08 Protein, wu:fk65d12 Protein, gnb2-rs1 Protein, h12.3 Protein, hlc-7 Protein, pig21 Protein, C12-3 Protein, c12.3 Protein, guanine nucleotide binding protein, beta 2, related sequence 1 Protein, receptor for activated C kinase 1 Protein, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 Protein, receptor for activated C kinase 1 L homeolog Protein, Guanine nucleotide-binding protein subunit beta-2-like 1 Protein, gnb2l1 Protein, RACK1 Protein, Rack1 Protein, rack1.L Protein, rack-1 Protein
    背景
    GNB2L1 was originally identified as an anchoring protein for protein kinase C beta (PKCbeta), which it stabilises in the active state and anchors to membranes or functional sites. However, evidence has accumulated to support a central role of GNB2L1 in critical biological responses. In addition to binding specifically to the active form of PKCbeta isoforms, GNB2L1 also interacts with several other important signaling proteins including the Src kinase family, integrin beta1, integrin beta2, integrin beta3 and integrin beta5, beta-spectrin and dynamin, RasGAP, the androgen receptor, insulin-like growth factor 1 receptor (IGF-1r), Epstein-Barr virus trans-activator protein BZLF1, p73 and pRB. GNB2L1 is ubiquitously expressed in the tissues of higher mammals and humans including brain, liver, and spleen. Recombinant human GNB2L1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Guanine nucleotide-binding protein subunit beta-2-like 1 , Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1. NCBI no.: NP_006089
    分子量
    37.2 kDa (337aa) confirmed by MALDI-TOF
    途径
    cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity
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