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NAE1 Protein (AA 1-534) (His tag)

NAE1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN668001
发货至: 中国
  • 抗原 See all NAE1 蛋白
    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-534
    宿主
    资源
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This NAE1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    NAE1, 1-534aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product NAE1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
    储存条件
    4 °C
  • 抗原
    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
    别名
    NAE1 (NAE1 产品)
    别名
    APPBP1 Protein, CG7828 Protein, Dmel\\CG7828 Protein, anon-WO0140519.225 Protein, dAPP-BP1 Protein, dAPPBP1 Protein, A-116A10.1 Protein, ula-1 Protein, Appbp1 Protein, 59kDa Protein, appbp1 Protein, zgc:66148 Protein, beta-Amyloid precursor protein binding protein 1 Protein, NEDD8 activating enzyme E1 subunit 1 Protein, NEDD8 activating enzyme E1 subunit 1 S homeolog Protein, nedd8 activating enzyme E1 subunit 1 Protein, NEDD8-activating enzyme E1 regulatory subunit Protein, APP-BP1 Protein, NAE1 Protein, Nae1 Protein, nae1.S Protein, nae1 Protein, ula-1 Protein
    背景
    NAE1 (NEDD8-activating enzyme E1 regulatory subunit) belongs to the ubiquitin-activating E1 family. This protein binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. NAE1 participates in a novel ubiquitinylation-related pathway involving the ubiquitin-like molecule NEDD8. Also, this protein is required for cell cycle progression through the S/M checkpoint. Recombinant human NAE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NEDD8 activating enzyme E1 subunit 1, A-116A10.1, APPBP1, HPP1, ula-1. NCBI no.: NP_003896
    分子量
    62.7kDa (557aa)
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