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DDIT4 Protein (AA 1-232) (His tag)

DDIT4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667871
发货至: 中国
  • 抗原 See all DDIT4 蛋白
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    蛋白类型
    Recombinant
    产品特性
    AA 1-232
    宿主
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This DDIT4 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    DDIT4, 1-232aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
    储存条件
    4 °C
  • 抗原
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    别名
    DDIT4 (DDIT4 产品)
    别名
    redd1 Protein, Dig2 Protein, REDD-1 Protein, REDD1 Protein, 5830413E08Rik Protein, AA415483 Protein, Rtp801 Protein, dig2 Protein, rtp801 Protein, sb:cb821 Protein, zgc:64114 Protein, DNA damage inducible transcript 4 Protein, DNA-damage-inducible transcript 4 Protein, DNA damage inducible transcript 4 S homeolog Protein, ddit4 Protein, DDIT4 Protein, Ddit4 Protein, ddit4.S Protein
    背景
    DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level. DDIT4 negatively regulates the mammalian target of Rapamycin, a serine/threonine kinase often referred to as mTOR. It is crucial in the coupling of extra- and intracellular cues to mTOR regulation. Recombinant human DDIT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801. NCBI no.: NP_061931
    分子量
    27.5 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    途径
    Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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