SCO2 Protein (AA 42-266) (His tag)
-
- 抗原 See all SCO2 蛋白
- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 42-266
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This SCO2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- SCO2, 42-266aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SCO2 蛋白
-
SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-266) protein (GST tag)
SCO2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 167-266) protein (GST tag)SCO2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 43-266) protein (His-SUMO Tag)SCO2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 2mM DTT, 200mM NaCl
- 储存条件
- 4 °C
-
- 抗原
- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
- 别名
- SCO2 (SCO2 产品)
- 别名
- CEMCOX1 Protein, MYP6 Protein, SCO1L Protein, SCO cytochrome oxidase deficient homolog 2 (yeast) Protein, SCO2 cytochrome c oxidase assembly protein Protein, SCO2, cytochrome c oxidase assembly protein Protein, SCO2 Protein, Sco2 Protein
- 背景
- SCO2 protein belongs to the SCO1/2 family of proteins. Both SCO1 and SCO2 proteins are located on the inner membrane of the mitochondria and plays a crucial role in copper insertion or transport to the active site of cytochrome c oxidase (COX). Defects in SCO2 are the cause of fatal infantile cardioencephalomyopathy with cytochrome c oxidase deficiency (FIC). This disease is characterized by hypertrophic cardiomyopathy, lactic acidosis, and gliosis. Heart and skeletal muscle show reductions in cytochrome c oxidase (COX) activity, whereas liver and fibroblasts show mild COX deficiencies. Recombinant human SCO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Protein SCO2 homolog mitochondrial, SCO1L. NCBI no.: NP_005129
- 分子量
- 27.4kDa (246aa), confirmed by MALDI-TOF
- 途径
- Transition Metal Ion Homeostasis, Warburg Effect
-
