DCK Protein (AA 1-260) (His tag)
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- 抗原 See all DCK 蛋白
- DCK (Deoxycytidine Kinase (DCK))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-260
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This DCK protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- DCK, 1-260aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DCK 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 0.1 mM PMSF, 2mM EDTA, 10% Glycerol
- 储存条件
- 4 °C
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- 抗原
- DCK (Deoxycytidine Kinase (DCK))
- 别名
- DCK (DCK 产品)
- 别名
- dck Protein, DCK Protein, wu:fc15f06 Protein, zgc:101771 Protein, dck1 Protein, deoxycytidine kinase Protein, deoxycytidine kinase, gene 2 L homeolog Protein, deoxycytidine kinase, gene 2 Protein, Deoxycytidine kinase Protein, deoxycytidine kinase, gene 1 L homeolog Protein, DCK Protein, dck Protein, dck.2.L Protein, dck.2 Protein, Dck Protein, FPV059 Protein, FPV151 Protein, dck.1.L Protein
- 背景
- DCK is a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant nucleoside analogues. This protein is responsible for the 5`-phosphorylation of purine and pyrimidine deoxynucleosides to the corresponding monophosphates using ATP or UTP as phosphate donors. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. Recombinant human DCK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: MGC117410, MGC138632, Deoxycytidine kinase. NCBI no.: NP_000779
- 分子量
- 34.6 kDa(296aa), confirmed by MALDI-TOF
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