BAG3 Protein (AA 1-575) (His tag)
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- 抗原 See all BAG3 蛋白
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-575
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This BAG3 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- BAG3, 1-575aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BAG3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM EDTA, 0.1mM PMSF, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- 别名
- BAG3 (BAG3 产品)
- 别名
- bag3-A Protein, MGC53113 Protein, zgc:100859 Protein, BAG3 Protein, ATBAG3 Protein, BCL-2-associated athanogene 3 Protein, T28J14.160 Protein, T28J14_160 Protein, BAG-3 Protein, BIS Protein, CAIR-1 Protein, MFM6 Protein, AA407278 Protein, Bis Protein, mg638 Protein, BCL2 associated athanogene 3 L homeolog Protein, BCL2-associated athanogene 3 Protein, BCL2 associated athanogene 3 Protein, BCL-2-associated athanogene 3 Protein, Bcl2-associated athanogene 3 Protein, bag3.L Protein, bag3 Protein, BAG3 Protein, Bag3 Protein
- 背景
- BAG3 was reported initially as a protein-refolding cochaperone of the bcl2 binding protein BAG family and as upregulated in response to persistent stress of cellular calcium balance dysregulation. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Also, it has been shown to diminish stress-induced apoptosis. Recombinant human BAG3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: BIS, CAIR-1, BAG family molecular chaperone regulator 3 BAG 3, Bcl 2 binding protein, BCL2 associated athanogene 3, BCL2 binding athanogene 3, Docking protein CAIR 1. NCBI no.: NP_004272
- 分子量
- 63.7 kDa (595aa)
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