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DTNBP1 Protein (AA 1-270) (His tag)

DTNBP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667731
发货至: 中国
  • 抗原 See all DTNBP1 蛋白
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-270
    宿主
    • 7
    • 2
    • 2
    • 1
    • 1
    资源
    • 3
    • 3
    • 2
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This DTNBP1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    Dysbindin, 1-270aa, Human, His-tagged, Recombinant, E.coli
    纯度
    > 95 % by SDS - PAGE
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    In 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 0.5mM DTT, 20% glycerol
    储存条件
    4 °C
  • 抗原
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    别名
    Dysbindin (DTNBP1 产品)
    别名
    5430437B18Rik Protein, AW048963 Protein, Bloc1s8 Protein, dysbindin Protein, sdy Protein, BLOC1S8 Protein, DBND Protein, HPS7 Protein, My031 Protein, SDY Protein, dtnbp1 Protein, zgc:56462 Protein, MGC83903 Protein, dbnd Protein, hps7 Protein, my031 Protein, MGC85477 Protein, DTNBP1 Protein, CG6856 Protein, Ddysb Protein, Dmel\\CG6856 Protein, si:ch211-285p6.1 Protein, dystrobrevin binding protein 1 Protein, Dysbindin Protein, dystrobrevin binding protein 1a Protein, dystrobrevin binding protein 1 L homeolog Protein, dystrobrevin binding protein 1 S homeolog Protein, dystrobrevin binding protein 1b Protein, Dtnbp1 Protein, DTNBP1 Protein, dtbp1 Protein, dtnbp1a Protein, dtnbp1.L Protein, dtnbp1.S Protein, dtnbp1 Protein, Dysb Protein, dtnbp1b Protein
    背景
    Dysbindin is a ubiquitously expressed protein that binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex (DPC) in both muscle and nonmuscle cells. Dysbindin has been strongly implicated in schizophrenia (SZ) susceptibility by a series of independent genetic association and gene expression studies. Among its known functions, dysbindin is part of a protein complex, termed the biogenesis of lysosome-related organelles complex 1 (BLOC-1), the molecular components of which might be involved in the regulation of vesicular trafficking and dendrite branching. Dysbindin effects for brain volume and cortical thickness appear driven by different neurobiological processes. Recombinant human Dysbindin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: DTNBP1, DBND, HPS7, SDY, Dystrobrevin-binding protein 1 isoform C Dystrobrevin binding protein 1, Hermansky Pudlak syndrome 7 protein. NCBI no.: NP_898862
    分子量
    34.6 kDa (307aa), confirmed by MALDI-TOF.
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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