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HMBS Protein (AA 1-361) (His tag)

HMBS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667690
发货至: 中国
  • 抗原 See all HMBS 蛋白
    HMBS (Hydroxymethylbilane Synthase (HMBS))
    蛋白类型
    Recombinant
    产品特性
    AA 1-361
    宿主
    • 8
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
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    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This HMBS protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    HMBS, 1-361aa , Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HMBS 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
    储存条件
    4 °C
  • 抗原
    HMBS (Hydroxymethylbilane Synthase (HMBS))
    别名
    HMBS (HMBS 产品)
    别名
    PBG-D Protein, PBGD Protein, PORC Protein, UPS Protein, URO-S Protein, hemC Protein, pbg-d Protein, pbgd Protein, ups Protein, SPAC806.01 Protein, DDBDRAFT_0186148 Protein, DDBDRAFT_0231417 Protein, DDB_0186148 Protein, DDB_0231417 Protein, Hmbs Protein, NV50236 Protein, T25658 Protein, Ups Protein, Uros1 Protein, hmbs Protein, zgc:64128 Protein, hmbsl Protein, id:ibd5004 Protein, im:7140060 Protein, zgc:110690 Protein, hydroxymethylbilane synthase Protein, hydroxymethylbilane synthase S homeolog Protein, hydroxymethylbilane synthase L homeolog Protein, hydroxymethylbilane synthase (predicted) Protein, Hydroxymethylbilane synthase Protein, hydroxymethylbilane synthase a Protein, hydroxymethylbilane synthase, b Protein, HMBS Protein, Hmbs Protein, hmbs Protein, hmbs.2.S Protein, hmbs.L Protein, CNC02250 Protein, hem3 Protein, hemC Protein, Trad_0335 Protein, Plabr_2100 Protein, Sgly_3113 Protein, SMLT_RS19660 Protein, PMI_RS16580 Protein, hmbsa Protein, hmbsb Protein
    背景
    Porphobilinogen deaminase, also known as HMBS, is a member of the hydroxymethylbilane synthase superfamily. It is a cytoplasmic enzyme found in the heme synthesis pathway. Deficiency of HMBS causes errors in pyrrole metabolism which in turn leads to an inherited autosomal disorder called acute intermittent porphyria (AIP) which is characterized by acute attacks of neurological dysfunctions with hypertension, tachycardia, peripheral neurologic disturbances, abdominal pain and excessive amounts of aminolevulinic acid and porphobilinogen in the urine. Recombinant human HMBS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PBG-D, PBGD, PORC, UPS. NCBI no.: NP_000181
    分子量
    41.9kDa (385aa) confirmed by MALDI-TOF
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