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CDKN2C Protein (AA 1-168) (His tag)

CDKN2C 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667655
发货至: 中国
  • 抗原 See all CDKN2C 蛋白
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    蛋白类型
    Recombinant
    产品特性
    AA 1-168
    宿主
    • 7
    • 1
    资源
    • 4
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CDKN2C protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    CDKN2C, 1-168aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CDKN2C 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
    储存条件
    4 °C
  • 抗原
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    别名
    CDKN2C (CDKN2C 产品)
    别名
    CDKN2C Protein, p18 Protein, ink4c Protein, p18-ink4c Protein, INK4C Protein, p18-INK4C Protein, C77269 Protein, INK4c Protein, INK4d Protein, p18INK4c Protein, cyclin dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Protein, CDKN2C Protein, cdkn2c Protein, Cdkn2c Protein
    背景
    CDKN2C (Cyclin-dependent kinase 4 inhibitor C ) belongs to the CDKN2 cyclin-dependent kinase inhibitor family. It has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. And this protein suppresses the cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Recombinant human CDKN2C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cyclin-dependent kinase 4 inhibitor C, INK4C, p18, p18-INK4C. NCBI no.: NP_001253
    分子量
    20.7kDa (192aa), confirmed by MALDI-TOF
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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