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RAB32 Protein (AA 1-225) (His tag)

RAB32 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667585
发货至: 中国
  • 抗原 See all RAB32 蛋白
    RAB32 (RAB32, Member RAS Oncogene Family (RAB32))
    蛋白类型
    Recombinant
    产品特性
    AA 1-225
    宿主
    • 5
    • 1
    资源
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This RAB32 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    RAB32, 1-225aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product RAB32 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 200mM NaCl, 2mM EDTA
    储存条件
    4 °C
  • 抗原
    RAB32 (RAB32, Member RAS Oncogene Family (RAB32))
    别名
    RAB32 (RAB32 产品)
    别名
    cb914 Protein, hm:zehn1770 Protein, rab32 Protein, zgc:110481 Protein, MGC130912 Protein, RAB32 Protein, LOC100224194 Protein, 2810011A17Rik Protein, AU022057 Protein, RGD1559997 Protein, RAB32a, member RAS oncogene family Protein, RAB32, member RAS oncogene family Protein, RAB32, member RAS oncogene family S homeolog Protein, rab32a Protein, rab32 Protein, RAB32 Protein, rab32.S Protein, Rab32 Protein
    背景
    RAB32 belongs to the small GTPase superfamily. RAB32 modulates ER calcium handling and disrupts the specific enrichment of calnexin on the MAM (mitochondria-associated membrane), while not affecting the ER distribution of protein-disulfide isomerase and mitofusin-2. Also, RAB32 determines the targeting of PKA (cAMP-dependent protein kinase) to mitochondrial and ER membranes and through its overexpression or inactivation increases the phosphorylation of Bad and of Drp1. Through a combination of its functions as a PKA-anchoring protein and a regulator of MAM properties, the activity and expression level of RAB32 determine the speed of apoptosis onset. Recombinant human RAB32 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Ras-related protein Rab-32,. NCBI no.: NP_006825
    分子量
    27.6kDa (249aa), confirmed by MALDI-TOF
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