CLCF1 Protein (AA 28-225) (His tag)
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- 抗原 See all CLCF1 蛋白
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 28-225
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This CLCF1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- CLCF1, 28-225aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. 20mM sodium citrate (pH 3.5), 0.4M Urea, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- 别名
- CLCF1 (CLCF1 产品)
- 别名
- clc Protein, nr6 Protein, bsf3 Protein, nnt1 Protein, ciss2 Protein, CLCF1 Protein, BSF-3 Protein, BSF3 Protein, CISS2 Protein, CLC Protein, NNT-1 Protein, NNT1 Protein, NR6 Protein, Bsf3 Protein, Clc Protein, cardiotrophin like cytokine factor 1 Protein, cardiotrophin-like cytokine factor 1 Protein, clcf1 Protein, CLCF1 Protein, Clcf1 Protein
- 背景
- CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Synonyms: Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6. NCBI no.: NP_037378
- 分子量
- 24.6 kDa (219aa)
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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