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Sntn Protein (AA 1-147) (His tag)

Sntn 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667444
发货至: 中国
  • 抗原 See all Sntn 蛋白
    Sntn (Sentan, Cilia Apical Structure Protein (Sntn))
    蛋白类型
    Recombinant
    产品特性
    AA 1-147
    宿主
    • 2
    • 1
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Sntn protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    SNTN, 1-147aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product Sntn 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 0.15M NaCl, 1mM DTT
    储存条件
    4 °C
  • 抗原
    Sntn (Sentan, Cilia Apical Structure Protein (Sntn))
    别名
    SNTN (Sntn 产品)
    别名
    S100A1L Protein, S100AL Protein, sentan Protein, A430083B19Rik Protein, sentan, cilia apical structure protein Protein, SNTN Protein, Sntn Protein
    背景
    SNTN, also known as sentan, belongs to the S-100 family. SNTN is shown to localize exclusively to the bridging structure between the cell membrane and peripheral singlet microtubules, which specifically exists in the narrowed distal portion of cilia. Exogenously expressed sentan showed affinity for the membrane protrusions, and a protein-lipid binding assay revealed that sentan bound to phosphatidylserine. These findings suggest that sentan is the first molecular component of the ciliary tip to bridge the cell membrane and peripheral singlet microtubules, making the distal portion of the cilia narrow and stiff to allow for better airway clearance or ovum transport. Recombinant human SNTN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Sentan, S100A1L, S100AL. NCBI no.: NP_001074006
    分子量
    18.6 kDa (167aa), confirmed by MALDI-TOF
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