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MLF1 Protein (AA 1-268) (His tag)

MLF1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN667346
发货至: 中国
  • 抗原 See all MLF1 蛋白
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-268
    宿主
    • 2
    • 1
    • 1
    • 1
    资源
    • 2
    • 1
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    • 1
    大肠杆菌(E. Coli)
    标记
    This MLF1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    MLF1, 1-268aa, Human, His tag, E.coli
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product MLF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl
    储存条件
    4 °C
  • 抗原
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    别名
    MLF1 (MLF1 产品)
    别名
    MLF1 Protein, HLS7 Protein, myeloid leukemia factor 1 Protein, myeloid leukemia factor 1 L homeolog Protein, MLF1 Protein, mlf1.L Protein, mlf1 Protein, Mlf1 Protein
    背景
    MLF1 (Myeloid leukemia factor 1) belongs to MLF family, and is a widely expressed negative regulator of cell cycle progression functioning upstream of the tumor suppressor p53. This protein interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 normally functions in multi-potent progenitor cells, and its dysregulation may be somewhat responsible for leukemogenesis. Recombinant human MLF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Myeloid leukemia factor 1,. NCBI no.: NP_071888
    分子量
    32.8kDa (288aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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