BPNT1 Protein (AA 1-308) (His tag)
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- 抗原 See all BPNT1 蛋白
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-308
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This BPNT1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- BPNT1, 1-308aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS – PAGE
- Top Product
- Discover our top product BPNT1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 5mM DTT, 0.1M NaCl.
- 储存条件
- 4 °C
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- 抗原
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- 别名
- BPNT1 (BPNT1 产品)
- 别名
- BPNT1 Protein, PIP Protein, Sal3 Protein, BPntase Protein, 3'(2'), 5'-bisphosphate nucleotidase 1 Protein, bisphosphate 3'-nucleotidase 1 Protein, BPNT1 Protein, bpnt1.L Protein, Bpnt1 Protein
- 背景
- BPNT1, also known as BPntase, PAP phosphatase or PIP (PAP-inositol-1,4-phosphatase), is a member of the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. Using magnesium as a cofactor, BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate). Expressed ubiquitously with highest levels in brain and kidney, BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, suggesting a possible role for BPNT1 in the etiology of mood disorders. Recombinant human BPNT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: 3'(2'), 5'-bisphosphate nucleotidase 1, PIP, PAP-inositol-1,4-phosphatase. NCBI no.: NP_006076
- 分子量
- 37.5 kDa (344aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- 途径
- Inositol Metabolic Process
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