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BPNT1 Protein (AA 1-308) (His tag)

BPNT1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS – PAGE SDS
产品编号 ABIN667334
发货至: 中国
  • 抗原 See all BPNT1 蛋白
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-308
    宿主
    • 6
    • 2
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This BPNT1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    BPNT1, 1-308aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS – PAGE
    Top Product
    Discover our top product BPNT1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 5mM DTT, 0.1M NaCl.
    储存条件
    4 °C
  • 抗原
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    别名
    BPNT1 (BPNT1 产品)
    别名
    BPNT1 Protein, PIP Protein, Sal3 Protein, BPntase Protein, 3'(2'), 5'-bisphosphate nucleotidase 1 Protein, bisphosphate 3'-nucleotidase 1 Protein, BPNT1 Protein, bpnt1.L Protein, Bpnt1 Protein
    背景
    BPNT1, also known as BPntase, PAP phosphatase or PIP (PAP-inositol-1,4-phosphatase), is a member of the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. Using magnesium as a cofactor, BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate). Expressed ubiquitously with highest levels in brain and kidney, BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, suggesting a possible role for BPNT1 in the etiology of mood disorders. Recombinant human BPNT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: 3'(2'), 5'-bisphosphate nucleotidase 1, PIP, PAP-inositol-1,4-phosphatase. NCBI no.: NP_006076
    分子量
    37.5 kDa (344aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    途径
    Inositol Metabolic Process
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