MGC78895 Protein, DSMA5 Protein, HSJ-1 Protein, HSJ1 Protein, HSPF3 Protein, 2700059H22Rik Protein, Dnajb10 Protein, Hsj1 Protein, mDj8 Protein, DnaJ heat shock protein family (Hsp40) member B2 L homeolog Protein, DnaJ heat shock protein family (Hsp40) member B2 Protein, dnajb2.L Protein, DNAJB2 Protein, dnajb2 Protein, Dnajb2 Protein
背景
DnaJB2, also known as HSJ1 or HSPF3, is belongs to the DnaJ family. It is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The DnaJ proteins play a critical role in the HSP70 chaperone machine by interacting with HSP70 to stimulate ATP hydrolysis. DnaJB2 is important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. Recombinant human DNAJB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DnaJ homolog subfamily B member 2, HSJ1, HSPF3. NCBI no.: NP_001034639
分子量
33 kDa (300aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)