PNP Protein (AA 1-289) (His tag)
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- 抗原 See all PNP (NP) 蛋白
- PNP (NP) (Nucleoside Phosphorylase (NP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-289
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This PNP protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- PNP, 1-289aa, Human, His tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NP 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 2mM DTT, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- PNP (NP) (Nucleoside Phosphorylase (NP))
- 别名
- PNP (NP 产品)
- 别名
- NP Protein, PRO1837 Protein, PUNP Protein, Np Protein, AL024301 Protein, AU015798 Protein, Np-1 Protein, Np-2 Protein, Pnp1 Protein, purine nucleoside phosphorylase Protein, purine-nucleoside phosphorylase Protein, PNP Protein, Pnp Protein
- 物质类
- Viral Protein
- 背景
- PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Recombinant human PNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PUNP. NCBI no.: NP_000261
- 分子量
- 34.2 kDa (309aa) confirmed by MALDI-TOF
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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