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MSRB1 Protein (AA 1-116) (His tag)

SEPX1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667227
发货至: 中国
  • 抗原 See all MSRB1 (SEPX1) 蛋白
    MSRB1 (SEPX1) (Selenoprotein X, 1 (SEPX1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-116
    宿主
    • 5
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    资源
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    大肠杆菌(E. Coli)
    标记
    This MSRB1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    SEPX1, 1-116aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SEPX1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 0.1 mM PMSF, 2mM EDTA, 10% Glycerol
    储存条件
    4 °C
  • 抗原
    MSRB1 (SEPX1) (Selenoprotein X, 1 (SEPX1))
    别名
    SEPX1 (SEPX1 产品)
    别名
    MsrB Protein, MsrB1-A Protein, SePR Protein, SelX-A Protein, cb687 Protein, selx Protein, sepx1 Protein, sepx1a Protein, wu:fa03e09 Protein, SEPX1 Protein, SELR Protein, SELX Protein, SepR Protein, D17Wsu82e Protein, SelR Protein, Sepr Protein, Sepx1 Protein, selX Protein, MSRB1 Protein, DKFZp469G2418 Protein, methionine sulfoxide reductase B1a Protein, methionine sulfoxide reductase B1 Protein, selenoprotein X, 1 Protein, msrb1a Protein, MSRB1 Protein, msrb1 Protein, Sepx1 Protein, Msrb1 Protein
    背景
    SEPX1, also known as Methionine sulfoxide reductase B1 (MSRB1), is a selenoprotein. Methionine sulfoxide reductases(MSRs) catalyze reduction of free and protein-bound methionine sulfoxides to corresponding methionines. The oxidation of methionine by ROS generates a diastereomeric mixture of methionine-S-sulfoxide (Met-S-SO) and methionine-R-sulfoxide (Met-R-SO). Two distinct enzyme families evolved for reduction of these sulfoxides, with methionine-S-sulfoxide reductase (MsrA) being stereospecific for Met-S-SO and methionine-R-sulfoxide reductase (MsrB) for Met-R-SO. In bacteria, the selenocystein (Sec/U) element is located immediately following the UGA codon within the reading frame for the selenoprotein so we mutated Sec-95 to Cys. Recombinant human SEPX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Selenoprotein X, HSPC270, MSRB1, SELR, SELX, MSRB1, Methionine-R-sulfoxide reductase B1, U95C. NCBI no.: NP_057416
    分子量
    14.8 kDa(136aa), confirmed by MALDI-TOF
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