HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) protein (His tag)
-
- 抗原 See all HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) 蛋白
- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-242
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- His tag
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- HTATIP2, 1-242aa, Human, His tag, E.coli
- 纯度
- > 95 % by SDS- PAGE
- Top Product
- Discover our top product HTATIP2 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
- 储存条件
- 4 °C
-
- 抗原
- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
- 别名
- HTATIP2 (HTATIP2 产品)
- 别名
- htatip2 Protein, MGC89074 Protein, HTATIP2 Protein, fb15b04 Protein, tip30 Protein, wu:fb15b04 Protein, CC3 Protein, SDR44U1 Protein, TIP30 Protein, AW111545 Protein, Cc3 Protein, Tip30 Protein, HIV-1 Tat interactive protein 2 Protein, HIV-1 Tat interactive protein 2 L homeolog Protein, HTATIP2 Protein, htatip2 Protein, Htatip2 Protein, htatip2.L Protein
- 物质类
- Viral Protein
- 背景
- HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CC3, TIP30, SDR44U1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30. NCBI no.: AAH15358
- 分子量
- 29.3 kDa (262aa), confirmed by MALDI-TOF
-