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NCK1 Protein (AA 1-377) (His tag)

NCK1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667017
发货至: 中国
  • 抗原 See all NCK1 蛋白
    NCK1 (NCK Adaptor Protein 1 (NCK1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-377
    宿主
    • 6
    • 1
    资源
    • 4
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This NCK1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    NCK1, 1-377aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product NCK1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50mM NaCl
    储存条件
    4 °C
  • 抗原
    NCK1 (NCK Adaptor Protein 1 (NCK1))
    别名
    NCK1 (NCK1 产品)
    别名
    NCK Protein, NCKalpha Protein, nck-1 Protein, NCK1 Protein, 6330586M15Rik Protein, D230010O13Rik Protein, Nck Protein, Nck-1 Protein, Nck1 Protein, nck Protein, nck1-a Protein, nck1-b Protein, nckalpha Protein, NCK adaptor protein 1 Protein, non-catalytic region of tyrosine kinase adaptor protein 1 Protein, NCK adaptor protein 1b Protein, NCK adaptor protein 1 L homeolog Protein, NCK1 Protein, Nck1 Protein, nck1b Protein, nck1.L Protein
    背景
    NCK adaptor protein 1, also known as NCK, belongs to the adaptor family of proteins. The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Overexpression of Nck resulted in transformation of NIH 3T3 and 3Y1 rat fibroblast. Recombinant human NCK1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NCK, NCKalpha, NCK adaptor protein 1 GRB4, melanoma NCK protein, MGC12668, NCK adaptor protein 2, NCK tyrosine kinase, NCKbeta, non catalytic region of tyrosine kinase, noncatalytic region of tyrosine kinase, beta, SH2/SH3 adaptor protein NCK alpha, SH2/SH3 adaptor protein NCK beta. NCBI no.: NP_006144
    分子量
    45 kDa (397aa), confirmed by MALDI-TOF
    途径
    TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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