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SGTA Protein (AA 1-313) (His tag)

SGTA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE SDS
产品编号 ABIN666980
发货至: 中国
  • 抗原 See all SGTA 蛋白
    SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))
    蛋白类型
    Recombinant
    产品特性
    AA 1-313
    宿主
    • 5
    • 1
    • 1
    • 1
    资源
    • 2
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    • 1
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    大肠杆菌(E. Coli)
    标记
    This SGTA protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    SGTA, 1-313 aa, Human, His-tagged, Recombinant, E.coli
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product SGTA 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
    储存条件
    4 °C
  • 抗原
    SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))
    别名
    SGTA (SGTA 产品)
    别名
    sgta Protein, SGTA Protein, zgc:92462 Protein, SGT Protein, alphaSGT Protein, hSGT Protein, 5330427H01Rik Protein, AI194281 Protein, D10Ertd190e Protein, Sgt Protein, Stg Protein, small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha Protein, small glutamine rich tetratricopeptide repeat containing alpha Protein, small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta Protein, small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha L homeolog Protein, sgta Protein, SGTA Protein, sgtb Protein, sgta.L Protein, Sgta Protein
    背景
    SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. Recombinant SGTA protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: alphaSGT, hSGT, SGT, Small glutamine-rich tetratricopeptide repeat-containing protein alpha Small glutamine rich tetratricopeptide repeat TPR containing alpha, UBP, Vpu binding protein. NCBI no.: NP_003012
    分子量
    35.1 kDa (321aa), confirmed by MALDI-TOF
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