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PARP1 Protein (AA 662-1014)

PARP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE SDS
产品编号 ABIN666940
发货至: 中国
  • 抗原 See all PARP1 蛋白
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    蛋白类型
    Recombinant
    产品特性
    AA 662-1014
    宿主
    • 15
    • 4
    资源
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    产品特性
    PARP1, 662-1014aa, Human, E.coli
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product PARP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol 1mM DTT.
    储存条件
    4 °C
  • 抗原
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    别名
    PARP1 (PARP1 产品)
    别名
    ADPRT Protein, ADPRT 1 Protein, ADPRT1 Protein, ARTD1 Protein, PARP Protein, PARP-1 Protein, PPOL Protein, pADPRT-1 Protein, Adprt Protein, Parp-1 Protein, 5830444G22Rik Protein, AI893648 Protein, Adprp Protein, Adprt1 Protein, C80510 Protein, parp-1 Protein, sPARP-1 Protein, BEST:LD21673 Protein, CG17685 Protein, CG17696 Protein, CG17718 Protein, CG40411 Protein, D.PARP Protein, Dm.pARTa Protein, Dmel\\CG40411 Protein, LD21673.3prime Protein, PARP1 Protein, dPARP Protein, parp Protein, adprt1 Protein, padprt-1 Protein, ppol Protein, si:dkey-206f10.3 Protein, wu:fc60f12 Protein, zgc:110092 Protein, poly(ADP-ribose) polymerase 1 Protein, poly (ADP-ribose) polymerase 1 Protein, poly (ADP-ribose) polymerase family, member 1 Protein, Poly-(ADP-ribose) polymerase Protein, poly(ADP-ribose) polymerase 1 L homeolog Protein, PARP1 Protein, Parp1 Protein, Parp Protein, parp1.L Protein, parp1 Protein
    背景
    PARP1 is a nuclear DNA-binding zinc finger protein which can exist as a homo- or hetero-dimer, and is strongly activated by DNA strand breaks. This protein involved in chromatin architecture and DNA metabolism, and participates in protein modification to enhance or repress transcription. PARP1 also plays a role in other cellular processes, including cell proliferation and differentiation. PARP-1 deficiencies lead to chromosomal instability due to higher frequencies of chromosome fusions and aneuploidy, suggesting that poly(ADPribosyl)ation contributes to the efficient maintenance of genome integrity. Recombinant PARP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ADPRT, ADPRT1, pADPRT, pADPRT-1, PARP, PARP-1, PPOL, Poly (ADP-ribose) polymerase family, member 1 ADP ribosyltransferase (NAD+, poly (ADP ribose) polymerase), ADPRT 1, msPARP, NAD(+) ADP ribosyltransferase 1, pADPRT 1, PARP 1, PARP1, Poly (ADP ribose) polymerase 1, poly(ADP ribose) synthetase, poly(ADP ribosyl)transferase, Poly[ADP ribose] synthetase 1, sPARP 1, sPARP1. NCBI no.: AAH37545
    分子量
    39.6 kDa (354aa), confirmed by MALDI-TOF.
    途径
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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