TCL1A Protein (AA 1-114)
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- 抗原 See all TCL1A 蛋白
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-114
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- TCL1A, 1-114 aa, Human, Recombinant, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TCL1A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 50mM Tris-HCl buffer (pH7.5) containing 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- 别名
- TCL1A (TCL1A 产品)
- 别名
- TCL1A Protein, Tcl1a Protein, TCL1 Protein, Tcl1 Protein, T-cell leukemia/lymphoma 1A Protein, T cell lymphoma breakpoint 1 Protein, TCL1A Protein, Tcl1 Protein, Tcl1a Protein
- 背景
- TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A. NCBI no.: NP_001092195
- 分子量
- 13.4 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
- 途径
- Stem Cell Maintenance
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