Estrogen receptor binding site associated antigen 9, also known as EBAG9, is a type III transmembrane protein that is predominantly located in the Golgi. This protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers, such as advanced breast and prostate cancers. As the EBAG9 acts to inhibit the growth of receptor-binding cells and induced apoptosis of immune cells, cancer cells might evade immune surveillance. So immunodetection of EBAG9 expression can be a negative prognostic indicator. Recombinant human EBAG9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EB9, PDAF, RCAS1, Estrogen receptor binding site associated antigen 9, EBAG9, Estrogen receptor binding site associated, antigen 9 BAG9, Cancer associated surface antigen, Cancer associated surface antigen RCAS1, EBAG 9, Estrogen receptor binding fragment associated gene 9 protein, PDAF, RCAS 1, RCAS1, Receptor binding cancer antigen expressed on SiSo cells. NCBI no.: NP_004206
分子量
23.4 kDa (207 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)