Neutrophil Migration (NM) (AA 22-255) 蛋白
NM
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % by SDS - PAGE
SDS
1 image
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- 抗原
- Neutrophil Migration (NM)
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-255
- 宿主
- 人
- 资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- NCR, NKp46 ( Extracellular Ig-like domain , 22-255aa, human), Recombinant, E.coli
- 纯度
- > 95 % by SDS - PAGE
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In phosphate buffered saline (pH7.4), 1mM EDTA
- 储存条件
- 4 °C
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- 抗原
- Neutrophil Migration (NM)
- 别名
- NCR
- 别名
- GP130 Protein, NCR Protein, neutrophil migration Protein, NM Protein
- 背景
- A natural cytotoxicity receptor(NCR) NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors(NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. The three known NCRs include NKp46 and NKp30,which are expressed on circulating NKcells, and NKp44,which is expressed only on activating NK cells. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. The extracellular Ig-like domain of NKp46( 22-255aa) was overexpressed in E.coli, and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Synonyms: NCR1, LY94, NCR, NKp46 Extracellular Ig-like domain, Natural killer cell p46-related protein, hNKp46, NK-p46, NKp46, NK cell-activating receptor, Lymphocyte antigen 94 homolog, CD335 antigen, Natural cytotoxicity triggering receptor 1, Natural cytotoxicity triggering receptor 1 isoform a. NCBI no.: NP_004820
- 分子量
- 26.6 kDa (235 aa), confirmed by MALDI-TOF.
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