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GLUL Protein (AA 1-373) (His tag)

GLUL 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS Active
产品编号 ABIN6387882
发货至: 中国
  • 抗原 See all GLUL 蛋白
    GLUL (Glutamate-Ammonia Ligase (GLUL))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 1-373
    宿主
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    资源
    • 35
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    大肠杆菌(E. Coli)
    标记
    This GLUL protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE LKEALSEEIK KAQRTGA
    纯度
    > 90 % by SDS - PAGE
    Biological Activity Comment
    Specific activity is >100 units/mg and is defined as the amount of enzyme that convert 1.0 umole of GMP and ATP to GDP and ADP per minute at pH 7.5 at 37C in coupled system with PK/LDH.
    Top Product
    Discover our top product GLUL 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Bioactivity Validated

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer(  pH 8.0) containing 10 % glycerol, 1  mM DTT, 0.1M NaCl
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    GLUL (Glutamate-Ammonia Ligase (GLUL))
    别名
    GLUL (GLUL 产品)
    别名
    GLNS Protein, GS Protein, PIG43 Protein, PIG59 Protein, Glns Protein, glns Protein, glul Protein, pig43 Protein, pig59 Protein, xgs Protein, p42 Protein, MGC64262 Protein, cb195 Protein, cb757 Protein, etID49849.2 Protein, fb39g09 Protein, fd19d09 Protein, gso1 Protein, sb:cb195 Protein, wu:fb39g09 Protein, wu:fd19d09 Protein, fb11d08 Protein, gso2 Protein, hm:zehn1949 Protein, im:7153900 Protein, wu:fb11d08 Protein, glutamate-ammonia ligase Protein, glutamate-ammonia ligase (glutamine synthetase) Protein, type I glutamate--ammonia ligase Protein, glutamate-ammonia ligase L homeolog Protein, glutamate-ammonia ligase (glutamine synthase) Protein, glutamate-ammonia ligase (glutamine synthase) a Protein, glutamate-ammonia ligase (glutamine synthase) b Protein, GLUL Protein, Glul Protein, AMF_RS09530 Protein, glul.L Protein, glul Protein, CNA04370 Protein, glula Protein, glulb Protein
    背景
    GUK1, also known as GMK, belongs to the guanylate kinase family. This protein exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GUK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GUK1 is associated with pituitary adenocarcinomas, suggesting that GUK1 is involved in tumorigenesis. Recombinant human GUK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    23.9 kDa (217aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_000849
    UniProt
    Q16774
    途径
    Positive Regulation of Peptide Hormone Secretion
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