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CSTA Protein (AA 1-98) (His tag)

CSTA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS Active
产品编号 ABIN6387718
发货至: 中国
  • 抗原 See all CSTA 蛋白
    CSTA (Cystatin A (Stefin A) (CSTA))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 1-98
    宿主
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    资源
    • 11
    • 3
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CSTA protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MIPGGLSEAK PATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAG TNYYIKVRAG DNKYMHLKVF KSLPGQNEDL VLTGYQVDKN KDDELTGF
    纯度
    > 95 % by SDS - PAGE
    Biological Activity Comment
    The IC50 value is < 1.0nM. The inhibitory function of Cystatin A on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
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    Discover our top product CSTA 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Bioactivity Validated

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In 20 mM Tris-HCl buffer (  pH 8.0) containing 1  mM DTT, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    CSTA (Cystatin A (Stefin A) (CSTA))
    别名
    CSTA (CSTA 产品)
    别名
    AREI Protein, STF1 Protein, STFA Protein, CST Protein, CSTA Protein, ATCYSA Protein, FL3-27 Protein, T20B5.8 Protein, T20B5_8 Protein, cystatin A Protein, cystatin A Protein, cystatin A1 Protein, cystatin-A Protein, CSTA Protein, Csta1 Protein, Csta Protein, CYSA Protein, LOC100725920 Protein
    背景
    CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies Recombinant human CSTA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    13.1 kDa (118aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_005204
    UniProt
    P01040
    途径
    Response to Water Deprivation
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