HCV NS5a Protein (AA 2210-2306) (His tag)
HCV NS5a
宿主: Hepatitis C Virus (HCV)
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
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- 抗原 See all HCV NS5a products
- HCV NS5a (Hepatitis C Virus NS5a (HCV NS5a))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2210-2306
- 宿主
- Hepatitis C Virus (HCV)
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HCV NS5a protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MSLKATCTAN HDSPDAELIE ANLLWRQEMG GNITRVESEN KVVILDSFDP LVAEEDEREV SVPAEILRKS RRFARALPVW ARPDYNPPLV ETWKKPDY
- 纯度
- > 90 % by SDS - PAGE
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 40 % glycerol, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- HCV NS5a (Hepatitis C Virus NS5a (HCV NS5a))
- 别名
- HCV-NS5a (HCV NS5a 产品)
- 物质类
- Viral Protein
- 背景
- NS5A is a component of the replication complex involved in RNA-binding. Its interaction with Human VAPB may target the viral replication complex to vesicles. This protein down-regulates viral IRES translation initiation and mediates interferon resistance, presumably by interacting with and inhibiting human EIF2AK2/PKR. NS5a seems to inhibit apoptosis by interacting with BIN1 and FKBP8. The hyperphosphorylated form of NS5A is an inhibitor of viral replication. Recombinant HCV(Hepatitis C Virus) NS5A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 13.4 kDa (118aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_671491
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