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TARDBP Protein (His tag)

TARDBP 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098222
发货至: 中国
  • 抗原 See all TARDBP 蛋白
    TARDBP (TAR DNA Binding Protein (TARDBP))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 3
    • 1
    • 1
    资源
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TARDBP protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TARDBP 蛋白
  • 说明

    Synonyms: TAR DNA binding protein, ALS10, TDP43

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    TARDBP (TAR DNA Binding Protein (TARDBP))
    别名
    TARDBP (TARDBP 产品)
    别名
    TARDBP Protein, TDP43 Protein, DKFZp459I2127 Protein, tardbp Protein, ALS10 Protein, TDP-43 Protein, 1190002A23Rik Protein, C85084 Protein, Tdp43 Protein, wu:fb77f02 Protein, wu:fc52g10 Protein, TAR DNA binding protein Protein, Tardbp protein Protein, TAR DNA binding protein L homeolog Protein, TAR DNA-binding protein 43-like Protein, TARDBP Protein, tardbp Protein, tardbp.L Protein, Tardbp Protein, LOC100621383 Protein
    背景
    TARDBP was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Recombinant human TARDBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
    分子量
    33.6 kDa(296aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_031401
    途径
    Positive Regulation of Peptide Hormone Secretion
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