TBCC Protein (His tag)
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- 抗原 See all TBCC 蛋白
- TBCC (Tubulin Folding Cofactor C (TBCC))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TBCC protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TBCC 蛋白
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- 说明
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Synonyms: Tubulin-specific chaperone C, CFC, tubulin folding cofactor C
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- TBCC (Tubulin Folding Cofactor C (TBCC))
- 别名
- TBCC (TBCC 产品)
- 别名
- CFC Protein, 2810055C19Rik Protein, tubulin folding cofactor C Protein, tubulin-specific chaperone C Protein, TBCC Protein, Tbcc Protein
- 背景
- TBCC (tubulin folding cofactor C) belongs to the TBCC family. It is plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. Cofactor C is one of four proteins(cofactors A,D,E and C) involved in the pathway leading to correctly folded b-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing b-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/b-tubulin complex, interaction with cofactor C then causes the release of b-tubulin polypeptides. Recombinant human TBCC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 41.7 kDa (369aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_003183
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