RYBP Protein (His tag)
-
- 抗原 See all RYBP 蛋白
- RYBP (RING1 and YY1 Binding Protein (RYBP))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This RYBP protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product RYBP 蛋白
-
-
- 说明
-
Synonyms: RING1 and YY1 binding protein, AAP1, DEDAF, YEAF1
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer, pH 8.0, 20% glycerol, 1 MM DTT, 100 mM NaCl
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
-
- 抗原
- RYBP (RING1 and YY1 Binding Protein (RYBP))
- 别名
- RYBP (RYBP 产品)
- 别名
- AAP1 Protein, DEDAF Protein, YEAF1 Protein, 2410018J24Rik Protein, rybp Protein, aap1 Protein, dedaf Protein, yeaf1 Protein, cb337 Protein, wu:fi34f03 Protein, Dedaf Protein, zgc:153842 Protein, RING1 and YY1 binding protein Protein, RING1 and YY1 binding protein L homeolog Protein, RING1 and YY1 binding protein a Protein, RING1 and YY1 binding protein b Protein, RYBP Protein, Rybp Protein, rybp Protein, rybp.L Protein, rybpa Protein, rybpb Protein
- 背景
- RYBP (RING1- and YY1-binding protein) is a member of the polycomb group (PcG). This protein interacts with MDM2 and decreases MDM2-mediated p53 ubiquitination, leading to stabilization of p53 and an increase in p53 activity. RYBP induces cell-cycle arrest and is involved in the p53 response to DNA damage. RYBP has been shown to interact with RING1, YY1, Caspase 10, E2F3, E2F2, Mdm2, Abl gene and CBX2. Recombinant human RYBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 27.4kDa (252aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI登录号
- NP_036366
-