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PSMB7 Protein (AA 44-277) (His tag)

PSMB7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % by SDS - PAGE SDS
产品编号 ABIN6386905
发货至: 中国
  • 抗原 See all PSMB7 蛋白
    PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
    蛋白类型
    Recombinant
    产品特性
    AA 44-277
    宿主
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    资源
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    大肠杆菌(E. Coli)
    标记
    This PSMB7 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    PSMB7, 44-277aa, Human, His tag, E.coli
    纯度
    > 80 % by SDS - PAGE
    Top Product
    Discover our top product PSMB7 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    储存条件
    4 °C
  • 抗原
    PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
    别名
    PSMB7 (PSMB7 产品)
    别名
    DDBDRAFT_0185624 Protein, DDBDRAFT_0232933 Protein, DDB_0185624 Protein, DDB_0232933 Protein, AU020723 Protein, MC14 Protein, Z Protein, 20S proteasome subunit beta-7 Protein, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog Protein, proteasome subunit beta 7 Protein, proteasome (prosome, macropain) subunit, beta type, 7 Protein, proteasome (prosome, macropain) subunit, beta type 7 Protein, psmB7 Protein, psmb7.S Protein, PSMB7 Protein, Psmb7 Protein
    背景
    PSMB7, also known as proteasome subunit beta type-7, is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i. Recombinant human PSMB7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome subunit Z, Proteasome subunit beta type 7. NCBI no.: NP_002790
    分子量
    27.6 kDa (255aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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