MGC75796 Protein, MGC81924 Protein, ABBP-2 Protein, ABBP2 Protein, DJ9 Protein, Dj-9 Protein, EDJ Protein, ERdj3 Protein, ERj3 Protein, ERj3p Protein, PRO1080 Protein, UNQ537 Protein, hDj-9 Protein, 1810031F23Rik Protein, AL024055 Protein, Dj9 Protein, LRRGT00084 Protein, cb954 Protein, DnaJ heat shock protein family (Hsp40) member B11 Protein, DnaJ heat shock protein family (Hsp40) member B11 S homeolog Protein, DnaJ (Hsp40) homolog, subfamily B, member 11 Protein, dnajb11 Protein, DNAJB11 Protein, dnajb11.S Protein, Dnajb11 Protein
背景
DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. It serves as a co-chaperone for HSPA5 and binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. Recombinant human DNAJB11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DnaJ homolog subfamily B member 11, ABBP-2, ABBP2, DJ9, EDJ, ERdj3, ERj3, hDj9, HEDJ, PRO1080, UNQ537. NCBI no.: NP_057390