AIMP1, also known as EMPA2 or p43, is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Recombinant human AIMP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Aminoacyl tRNA synthase complex–interacting multifunctional protein 1 , EMAP2, EMAPII, p43, SCYE1. NCBI no.: NP_001135888
分子量
39.2 kDa (356aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)